Archive for the ‘psychiatry’ Category
Journal retracts antipsychotic study when all subjects’ PET scans turn out to be unreliable or invalid
The Journal of Psychiatric Research is retracting a 2010 paper claiming to show a relationship between quetiapine (Seroquel) and certain lab tests and brain scans, after it turns out the brain images were either unreliable or invalid.
Here’s the notice for “Relationship between dopamine D2 receptor occupancy, clinical response, and drug and monoamine metabolites levels in plasma and cerebrospinal fluid. A pilot study in patients suffering from first-episode schizophrenia treated with quetiapine”: Read the rest of this entry »
In a recent paper, “Translational evaluation of JNJ-18038683, a 5-HT7 receptor antagonist, on REM sleep and in major depressive disorder,” researchers with New Jersey-based Janssen Pharmaceuticals Inc. tested whether a potential drug code-named JNJ-18038683 that binds to a receptor linked to depression could actually help patients.
Turns out, the drug was a flop, but Read the rest of this entry »
We’ve been watching with interest an unfolding flap about a controversial 2003 paper in the Archives of Sexual Behavior (ASB) by a prominent mental health researcher, Robert Spitzer, which suggested that gays could be deprogrammed by so-called “reparative therapy” to change their sexual orientation.
Spitzer, who was instrumental in the effort to extradite homosexuality from the realm of mental illnesses, apparently had developed serious doubts about the validity of his paper, which has been cited 47 times, according to Thomson Scientific’s Web of Knowledge. His regrets came to light recently in a piece by Gabriel Arana, of The American Prospect, detailing his own unfortunate experience with “ex-gay” therapy. In his article, Arana says Spitzer requested that he
print a retraction of his 2001 study, “so I don’t have to worry about it anymore”? Read the rest of this entry »
The authors of a study allegedly showing that antidepressants prevent suicide have retracted it over unspecified errors. Here’s the notice:
At the request of the authors and in agreement with the Editor-in-Chief and Wiley-Blackwell, the following article “Antidepressant medication prevents suicide in depression”. Acta Psychiatr Scand 2010;122:454–460 has been retracted. The retraction has been requested and agreed due to unintentional errors in the analysis of the data presented.
The original paper linked “data on the toxicological detection of antidepressants in 18 922 suicides in Sweden 1992–2003″ to “registers of psychiatric hospitalization as well as registers with sociodemographic data.” It found: Read the rest of this entry »
Or not so original. Last November, the journal published a study by two California researchers which looked at the possible effects of post-traumatic stress disorder on physical well-being in older women – and found no evidence of such a link.
Six months later, the journal published the findings again.