Archive for the ‘genetics retractions’ Category
BMC Genomics has issued an expression of concern for a 2011 paper by a prominent Argentine chemist, Ariel Fernandez, whose work covers several disciplines — “His research spans representation theory in algebra, physical chemistry, molecular biophysics, and more recently, molecular evolution and drug discovery” — and institutions. And therein lies the tale.
Fernandez appeared as the first author of the article, titled “Subfunctionalization reduces the fitness cost of gene duplication in humans by buffering dosage imbalances,” along with a pair of researchers from Taiwan. Fernandez’s affiliations were listed as being with the Instituto Argentino de Matemática “Alberto P. Calderón”, CONICET (National Research Council of Argentina), in Buenos Aires, the Department of Computer Science at the University of Chicago, and the Morgridge Institute for Research, in Madison, Wisc.
According to the abstract:
HeLa — the cell line that has apparently taken over any number of others commonly used in science, suggesting that many researchers may not have been studying what they thought they were studying — is back in the news. This weekend, it was the DNA sequence of the cells that’s made headlines, with a quiet unpublishing of data.
As Rebecca Skloot, author of The Immortal Life of Henrietta Lacks — Lacks’s name is where “HeLa” comes from, as they’re her cells — wrote in the New York Times Sunday, a group of researchers at the European Molecular Biology Laboratory published an analysis of the HeLa cells’ genome on March 11 in G3: Genes, Genomes, Genetics, a new journal from the Genetics Society of America.
That genome, of course, could be very useful in research, given how widely used HeLa cells are. But the problem was Read the rest of this entry »
Joseph Hoffman, an animal behavior researcher at the University of Bielefeld in Germany says he got a “kind of odd” feeling as he read a recent paper on the transcriptome of the spotted seal. Let’s just call it deja vu.
The article, “Characterization of the spotted seal Phoca largha transcriptome using Illumina paired-end sequencing and development of SSR markers,” which appeared in Comparative Biochemistry and Physiology Part D: Genomics and Proteomics:
Paper with “missing or placed wrongly” controls retracted because there’s “no editorial mechanism to review the errors”
Here’s the notice for “Host-dependent effects of the 3′ untranslated region of turnip crinkle virus RNA on accumulation in Hibiscus and Arabidopsis,” by Weimin Li and Sek-Man Wong of National University of Singapore and Temasek Life Sciences Laboratory: Read the rest of this entry »
The FASEB Journal has retracted a 2012 paper by a group from the University of Alabama, Birmingham (UAB), looking at the role of a tumor-suppressing micro-RNA in pulmonary fibrosis. The retraction suggests the provenance of the data are in question, and we learned details of what went wrong.
A team of Swiss microbiologists has retracted their 2012 paper in PLoS One on the genetics of the TB mycobacterium after learning that the fusion protein they thought they’d used in their study was in fact a different molecule.
Here’s the retraction notice for the article, “A β-lactamase based reporter system for ESX dependent protein translocation in mycobacteria,” which has been cited once, according to Thomson Scientific’s Web of Knowledge: Read the rest of this entry »
Seyed Rasoul Mousavi, assistant professor in the department of electrical and computer engineering at the Isfahan University of Technology in Khomeynīshahr, Iran, has been working on a way to help biologists assemble genomes with as little information as possible.
Last year, Mousavi submitted a manuscript to the Journal of Theoretical Biology, received acceptance after peer review, and got proofs back to edit.
For technical reasons, Mousavi says his corrections didn’t make it into the final article published on Jan. 12, so the publishers issued a separate corrigendum with the editorial changes. Then, on Feb. 8, the publishers retracted the corrigendum that accompanied the original article. The retraction of the corrigendum reads: Read the rest of this entry »
Ron Wides, a biologist specializing in pattern development at Bar-Ilan University, Israel, and colleagues have retracted a paper published in Mechanisms of Development after his lab found that their technique to delete the Ten-a gene ended up deleting other nearby genes, too.
It was deletions of other genes, and not Ten-a, that killed the fruit flies, Wides concluded. His group had also concluded, erroneously, that Ten-a is what’s known as a “pair-rule” gene. Fruit fly embryos develop in stacked segments, like tubes of Pringles; pair-rule genes guide the development of alternating segments. Those other loci, and not Ten-a, caused lethality and caused the flies to develop improperly early, Wides concluded.
A partial retraction has joined the ten retractions and five corrections of Anil Potti’s papers, this one of a 2008 paper in Molecular Cancer Therapeutics. The move comes 14 months after the retraction of the Nature Medicine paper upon which much of the Molecular Cancer Therapeutics paper was based.
The authors of a paper published last September in Blood about alleged links between certain genes and Hodgkin’s lymphoma have retracted it, after realizing they’d made mistakes in their calculations.
The retraction notice for “Multiple HLA class I and II associations in classical Hodgkin lymphoma and EBV status defined subgroups,” dated January 20 and signed by all of the authors, clearly explains what went wrong, taking pains to note that there was no misconduct involved: Read the rest of this entry »