Archive for the ‘unreliable findings’ Category
No, not that Madoff.
We’re talking about Robert Madoff, editor of Diseases of the Colon & Rectum. His journal is pulling a 2012 paper by a group of authors in Spain who seem to have been unable to back up their findings when they were found to contain errors.
The article, “Perianal versus endoanal application of glyceryl trinitrate 0.4% ointment in the treatment of chronic anal fissure: results of a randomized controlled trial. Is this the solution to the headaches?” looked at what evidently is a significant side effect of nitroglycerin treatment for anal fissures: headaches. According to the abstract:
The journal Heart has retracted a 2012 meta-analysis after learning that two of the six studies included in the review contained duplicated data. Those studies, it so happens, were conducted by one of the co-authors.
The article, “Low sodium versus normal sodium diets in systolic heart failure: systematic review and meta-analysis,” came from an eclectic group of authors from the United States, Canada and Italy (the first author is listed as being at a Wegmans pharmacy in Ithaca, N.Y.). The paper, published online in August 2012, purported to find that: Read the rest of this entry »
Two cancer papers retracted because authors “are unable to guarantee the accuracy of some of the figures”
Denise Egan, of the Institute of Technology Tallaght in Dublin, and colleagues published “In vitro anti-tumour and cyto-selective effects of coumarin-3-carboxylic acid and three of its hydroxylated derivatives, along with their silver-based complexes, using human epithelial carcinoma cell lines” and “A study of the role of apoptotic cell death and cell cycle events mediating the mechanism of action of 6-hydroxycoumarin-3-carboxylatosilver in human malignant hepatic cells” in 2007.
The two notices say the same thing: Read the rest of this entry »
Nature is retracting a 2010 paper by a team from Princeton and Drexel on the workings of Plasmodium falciparum, which causes malaria in people. How that came about seems to have been a winding road.
The article — a research letter — titled “Branched tricarboxylic acid metabolism in Plasmodium falciparum,” came from the Princeton lab of Manuel Llinás. It purported to find that:
Back in January, we wrote about the retraction of a paper in the International Journal of Radiation Oncology *Biology* Physics, the first from that journal in its 38-year history.
At the time, the journal’s new editor, Anthony Zietman, of Mass General, told us that he was working on a second retraction. That one has arrived.
The paper, “High-Dose Conformal Radiotherapy Reduces Prostate Cancer–Specific Mortality: Results of a Meta-analysis,” came from a team of radiation oncologists in Brazil, and was published last August.
According to the retraction notice:
A German professor who claims to have developed “a self-consistent field theory which is used to derive at all known interactions of the potential vortex” will have at least two papers retracted, thanks to the scrutiny of a concerned economist.
The first retraction has already appeared, in DNA and Cell Biology, for a paper by Konstantin Meyl called “DNA and Cell Resonance: Magnetic Waves Enable Cell Communication.” The notice says nothing: Read the rest of this entry »
In late December, we reported on the retraction of a 2010 research letter in Emerging Infectious Diseases looking at the genetics of swine flu.
The notice in the journal, a CDC publication, indicated that the conclusions were in error, although it didn’t really say much more:
To the Editor: We would like to retract the letter entitled “Triple Reassortant Swine Influenza A (H3N2) Virus in Waterfowl,” which was published the April 2010 issue of Emerging Infectious Diseases (1). The nucleoprotein gene sequences from the viruses reported in that letter are very closely related to those from the earliest detected triple reassortant swine influenza viruses [CY095676 A/sw/Texas/4199–2/1998(H3N2)]. Although these viruses could have acquired a swine-origin segment, the branch lengths are quite short for 9 years of evolution. Therefore, we have withdrawn these 4 isolates from GenBank and subsequently retract this letter.
As it happens, there was more to the story.
A team of Swiss microbiologists has retracted their 2012 paper in PLoS One on the genetics of the TB mycobacterium after learning that the fusion protein they thought they’d used in their study was in fact a different molecule.
Here’s the retraction notice for the article, “A β-lactamase based reporter system for ESX dependent protein translocation in mycobacteria,” which has been cited once, according to Thomson Scientific’s Web of Knowledge: Read the rest of this entry »
The Circulation Journal, the official organ of the Japanese Circulation Society, is retracting two papers by Hiroaki Matsubara, lead researcher on the Kyoto Heart Study, for unreliable findings. Matsubara’s institution, Kyoto Prefectural University, confirmed to us last March that it was investigating the prominent cardiologist.
The work of Matsubara came into question last year when the American Heart Association issued an expression of concern for five papers the society published in its journals. Larry Husten, at Forbes/CardioBrief, reports today that the two retracted articles were “Effects of Valsartan on Cardiovascular Morbidity and Mortality in High-Risk Hypertensive Patients With New-Onset Diabetes Mellitus: Sub-Analysis of the KYOTO HEART Study,” published in September 2012; and “Enhanced cardiovascular protective effects of valsartan in high-risk hypertensive patients with left ventricular hypertrophy: Sub-analysis of the KYOTO HEART study,” which appeared in March 2011.