Two patch-clamping retractions in PNAS and the JCI after first author admits image manipulation

A group of cardiology researchers formerly of the University of Cologne has retracted two papers, after investigations into allegations of misconduct led to an admission of guilt by one of the lab’s junior members.

Here’s the first retraction, for “Connexin 43 acts as a cytoprotective mediator of signal transduction by stimulating mitochondrial K_ATP channels in mouse cardiomyocytes,” published last week in the Journal of Clinical Investigation:

Two new corrections for Utah group that retracted two Cell Metabolism papers for missing notebooks

We have an update on the case of a University of Utah lab that retracted two Cell Metabolism papers last month after a fired lab technician disposed of two lab notebooks without permission. The team has now corrected two other papers, one in Blood and the other in the Journal of Clinical Investigation.

Here’s the notice from Blood:

It’s all bad, it’s all good: JCI retracts for made-up data but authors stand behind work

The Journal of Clinical Investigation has retracted a 2010 article after the researchers acknowledged that the paper contained a substantial amount of manipulated or manufactured data.

How much bad data? Enough to sink seven figures. And the authors said they could not produce raw data in another 19 or so figures and four tables.

But, as the notice states, the researcher said that despite the retraction, they stand by the thrust of their article, “Sphingosine-1-phosphate receptor-2 deficiency leads to inhibition of macrophage proinflammatory activities and atherosclerosis in apoE-deficient mice:”

University of Perugia researcher faces trial for embezzlement, fraud following 13 retractions and Expressions of Concern

Stefano Fiorucci, a gastroenterology researcher at the University of Perugia in Italy, has been indicted for fraud and embezzlement, after a university investigation found that he had manipulated images in papers that he used to win about 2 million Euros in grant funding.

The case, which has so far resulted in four retractions and nine Expressions of Concern, has dragged on for several years. The trial is scheduled for July. It’s the first time that embezzlement charges have been brought against a scientist found to have committed fraud, according to reports in Umbria 24 and the Umbria Journal.

Fiorucci’s attorney, Stefano Bagianti, told Umbria 24 that there was