“Technical but fundamental errors” lead to retraction of brain tumor paper

The journal Neuro-Oncology has retracted a 2011 paper by a group of researchers in Japan who had purported to find a genetic mechanism for how fluorescence can be used to diagnose certain brain tumors.

The paper, “Enhanced expression of coproporphyrinogen oxidase in malignant brain tumors: CPOX expression and 5-ALA–induced fluorescence,” reported measurements using quantitative real-time (qRT)-PCR.

As the retraction notice explains:

Mislabeled sample leads to a chain reaction of physics retractions

Two different teams of physicists have retracted papers from Physical Review B after realizing that a sample used in the paper published first — and which formed the basis of the second paper — was mislabeled.

Here’s the notice for the first paper, “s-wave superconductivity in barium-doped phenanthrene as revealed by specific-heat measurements,” by Jianjun Ying of the University of Science and Technology of China, Hefei, and colleagues:

Authors retract CT scan-cancer paper, citing faulty data

A group of cancer researchers in Japan has retracted their 2011 paper in the journal Medicine. The reason: They seem to have had some trouble — well, perhaps a bit more than some — with their patient population.

The article, titled “Usefulness of systemic CT scanning in the detection of malignant lymphadenopathy,” came from the lab of Norio Komatsu, a hematologist at Juntendo University School of Medicine.

The paper’s no longer online, but we did find an abstract floating around:

Mitochondrial fission paper falls for fusing data from earlier work

A team of neuroscientists in Japan has lost their 2012 article in Brain Research for duplicating elements of a figure from a paper they’d published earlier that year in another journal.

The article, “Dynamic changes of mitochondrial fission proteins after transient cerebral ischemia in mice,” came from a lab at Okayama University. The last author was Koji Abe. According to the retraction notice:

Kenji Okajima retraction count grows to five

Kenji Okajima

We’ve been following the case of Kenji Okajima, a professor at Nagoya City University in Japan who was suspended for six months following an investigation into work in his lab. Bits of the story — including at least one other university investigation, and scrutiny of Okajima’s colleagues, one of whom was fired — have been dribbling out for almost two years since a retraction notice in the Journal of Neuroscience.

In all, it looks as Nagoya found evidence of misconduct in 19 papers. The Journal of Neuroscience retraction appeared in 2011, and another showed up in the Journal of Immunology last year. Now there are three more: One in Translational Research and two in Blood.

Here’s the notice from Translational Research:

Retraction count for gynecologic cancer researcher Takai grows to seven

Noriyuki Takai, a gynecologic cancer researcher at Oita University in Japan who retracted three papers last October, has four more retractions, these in Cancer Letters.

All but one of the notices reads as follows:

After three retractions, five expressions of concern, cardiologist Matsubara resigns post

Hiroaki Matsubara, a leading Japanese cardiology researcher who has had three papers retracted and another five subject to expressions of concern, has resigned from Kyoto Prefectural University, according to local media.

Mainichi Shimbun reports — according to our roughest of (Google) translations — that Kyoto Prefectural University accepted Matsubara’s resignation following an investigation. That investigation — which the university had told us about last year — revealed serious problems with 27 studies.

As we noted last March:

“False data” forces retraction of Carbon paper co-authored by postdoc who led to PI’s suspension

There’s a new retraction in the journal Carbon.

The case didn’t involve a Carbon copy — say, plagiarism or duplication — but rather an instance of fraud in a Japanese university, part of a larger case we covered last August.

Here’s the retraction notice for the paper, “The role of Fe species in the pyrolysis of Fe phthalocyanine and phenolic resin for preparation of carbon-based cathode catalysts,” which appeared in August 2010:

Study of blood pressure drug valsartan retracted

Hiroaki Matsubara, a prominent cardiologist with five Expressions of Concern and two retractions for his CV, has another retraction.

As Larry Husten, who first reported the retraction at Forbes, notes, the notice for 2009′s “Effects of valsartan on morbidity and mortality in uncontrolled hypertensive patients with high cardiovascular risks: KYOTO HEART Study,” which appeared in the European Heart Journal, says very little:

Shigeaki Kato notches fifth retraction

Shigeaki Kato

An endocrinologist who resigned from the University of Tokyo last March as the university was investigating his work has retracted another paper.

Here’s the notice for the paper by corresponding author Shigeaki Kato and colleagues in the Journal of Bone and Mineral Research: