Archive for the ‘belgium’ Category
The survey, by the Dutch science magazine Eos with the help of Joeri Tijdink, of VU University Medical Center in Amsterdam, and the Pascal Decroos Fund for Investigative Journalism, found that Read the rest of this entry »
A group of Belgian researchers has retracted two decade-old papers in Arthritis & Rheumatism following an investigation and court case.
The papers involved the use of the drug infliximab — sold by Johnson & Johnson as Remicade — to treat Sjögren’s syndrome, an auto-immune condition marked by the destruction of exocrine glands that secrete saliva and tears.
Infliximab is not approved for Sjögren’s. Although the two now-retracted studies suggested that it might be helpful, subsequent data did not support those findings.
Yesterday, we brought you news of a story in Belgium involving questions about whether a woman who gave birth following an ovarian transplant could have become pregnant without the transplant. The case, which led to a university investigation but no retraction, included allegations of theft and arson.
This morning, we were made aware of a request for a retraction from The Lancet related to other work by Jacques Donnez, the obstetrician-gynecologist at the center of the case. In 2004, Donnez and colleagues published what they said was the first pregnancy using frozen banked ovarian tissue in The Lancet. The paper has been cited hundreds of times, but not everyone agreed with Donnez et al’s assessment at the time. All but one of the authors of a Lancet letter — colleagues of Donnez’s at the Catholic University of Louvain — describing the perinatal follow-up of the woman now say they don’t either, and want to retract their letter.
In their letter requesting retraction, published in the journal on July 14, Corinne Hubinont and colleagues write that they “did not have access to the patient’s gynaecological records throughout the pregnancy,” but that “Recently, we had the opportunity to read the patient’s notes,” which include a progesterone measurement “omitted by Donnez and colleagues:” Read the rest of this entry »
Here’s our attempt at a summary: Jacques Donnez, chair of Catholic University of Louvain’s (UCL) gynecology department, and colleagues published two studies in Human Reproduction in 2010. One study claimed to show that a woman had given birth after undergoing chemotherapy for severe sickle cell disease and then getting an ovarian transplant from her sister.
The other of those studies, the authors noted, confirmed “data published earlier as a case report” in 2007. That case report of a woman with another type of anemia — the pregnancy only went as far as an embryo, which did not survive — garnered a good deal of attention, because, as New Scientist reported: Read the rest of this entry »